Integrating multi-parameter microscopy data: organization and plasticity of cancer metastasis. Peter Friedl M.D., Ph.D. 1 Radboud University Nijmegen Medical. Plasticity of cell migration determined by tissue organization Thereby, the density of the ECM determines the invasion mode of mesenchymal tumor cells. Tumour-cell invasion and migration: diversity and escape mechanisms. P Friedl Cancer invasion and the microenvironment: plasticity and reciprocity. P Friedl.

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